Which cells are considered the main types of phagocytes?

Phagocytes are a vital component of the immune system, primarily responsible for engulfing and destroying pathogens and debris. Monocytes and neutrophils are considered the main types of phagocytes due to their direct involvement in the process of phagocytosis.

Monocytes are large white blood cells that circulate in the bloodstream and can differentiate into macrophages and dendritic cells upon migrating into tissues. Macrophages then actively engulf and digest pathogens, dead cells, and cellular debris. Neutrophils are the most abundant type of white blood cell and are typically the first responders to sites of infection; they quickly move to the area and perform phagocytosis to eliminate pathogens.

Eosinophils play a role in combating parasitic infections and are involved in allergic reactions, but they are not classified as primary phagocytes in the same way monocytes and neutrophils are. Therefore, the correct grouping of monocytes and neutrophils as main types of phagocytes aligns perfectly with their functions and roles in the immune response.